David Sinclair engagement report
@davidasinclair - 657K followers on X
Measured over 29 original posts from a 30-day window, last computed on August 25, 2026.
Engagement
A typical post picks up 595 interactions against 657K followers, an engagement rate of 0.091%. Measured over 29 original posts, its engagement rate beats 69% of 3,739 tracked accounts of a similar size, which puts it in the middle of its size range rather than at either end. Posts are seen about 84K times each, and 0.707% of those impressions turn into an interaction. That is about 12.8% of the follower count, which is the gap between an audience on paper and an audience in a timeline. Posting runs at about 2.9 posts a day over the last 30 days, with activity on roughly 73% of days. Most posts go out around 16:00 UTC, and Tuesday is the busiest day of the week. Of the 29 posts sampled, 62% carry an image or video, 17% are part of a thread and 45% link out. The account's strongest tracked post pulled 6.4K interactions, about 11x its own typical post. Recurring topics include #amputation, #regeneration.
Measured over 29 original posts from a 30-day window, last computed on August 25, 2026. Recurring tags: #amputation, #regeneration.
Compared with accounts its own size
David Sinclair's engagement rate beats 69% of the tracked X accounts closest to it in follower count (3,739 accounts, accounts of similar size (decile 8 of 10)). A percentile is spread evenly by construction, so 50 really is the middle of that group and 90 really is its top tenth.
On engagement per impression rather than per follower it beats 43% of the same group. When those two numbers disagree, the gap is about how far its posts travel rather than how people react to them.
Where this sits in the catalog
At 0.091%, David Sinclair sits above the 50th percentile of the 36,378 accounts in this comparison. That places it in the above the median band, which runs 0.08% to 0.432%.
Show the percentile table
| Percentile | Engagement rate |
|---|---|
| 10th percentile | 0.002% |
| 25th percentile | 0.012% |
| 50th percentile | 0.08% |
| 75th percentile | 0.432% |
| 90th percentile | 2.10% |
| 99th percentile | 161.0% |
This ruler is the whole measured catalog, not a size-matched group: it shows where the raw rate falls across every account we can measure, all of which are large. For a like-for-like comparison, read the size-band percentile above instead. See how the bands are built
Posting timing
This account posts most often around 16:00 UTC, and Tuesday is its busiest day of the week. The bars below are the catalog-wide pattern, with this account's own busiest slot marked. They do not show how this account performs at each hour: we keep one aggregate per account, not one per hour, so that measurement does not exist in our data.
Show engagement by hour posted, utc as a table
| Hour (UTC) | Vs author median | Posts |
|---|---|---|
| 00:00 UTC | -1% | 50K |
| 01:00 UTC | -2% | 51K |
| 02:00 UTC | -3% | 50K |
| 03:00 UTC | -4% | 53K |
| 04:00 UTC | -6% | 43K |
| 05:00 UTC | -4% | 42K |
| 06:00 UTC | -4% | 48K |
| 07:00 UTC | -5% | 52K |
| 08:00 UTC | -4% | 60K |
| 09:00 UTC | -3% | 69K |
| 10:00 UTC | -2% | 72K |
| 11:00 UTC | -3% | 78K |
| 12:00 UTC | -2% | 86K |
| 13:00 UTC | -2% | 94K |
| 14:00 UTC | -4% | 97K |
| 15:00 UTC | -2% | 100K |
| 16:00 UTC | -3% | 97K |
| 17:00 UTC | -2% | 90K |
| 18:00 UTC | -1% | 84K |
| 19:00 UTC | -2% | 79K |
| 20:00 UTC | -1% | 74K |
| 21:00 UTC | -1% | 66K |
| 22:00 UTC | -2% | 57K |
| 23:00 UTC | -2% | 51K |
Show engagement by day of week as a table
| Day | Vs author median | Posts |
|---|---|---|
| Sunday | +4% | 230K |
| Monday | 0% | 286K |
| Tuesday | -2% | 276K |
| Wednesday | -1% | 251K |
| Thursday | -1% | 244K |
| Friday | -3% | 252K |
| Saturday | +3% | 227K |
Best tweets
- Aug 12, 202611x their median
https://t.co/rUN1cPDY65
- Aug 8, 20269.3x their median
I’m incredibly proud & excited to finally share what we’ve been building for the past 3 years… https://t.co/rwNzbHYUiy is now live 🚀 In a world of conflicting health advice, how can anyone distinguish between what’s supported by science and what’s just opinion? I wanted to build something new. A place where scientists, engineers, industry leaders, and the public come together, where people can understand what the science actually says, and where we move healthcare beyond treating sickness toward extending healthy lifespan well beyond what’s currently possible. Explore the new Lifespan Magazine. Watch the Lifespan show. Ask scientists questions. Join a global community. And help support research and the next generation of scientists working to extend healthy human lifespan. I believe we’re at the beginning of a revolution in our understanding of human aging, and perhaps one day, our ability to change it. I want everyone to be part of it. Built by scientists. Built for you. https://t.co/rwNzbHYUiy Life’s too short. Let’s change that, together! 👊 —— Note: The views of Lifespan & its team are their own & do not represent the views of Harvard, Harvard Medical School, or their affiliates✌️
- Aug 3, 20263.7x their median
1/10 I'm a cardiologist. I've recommended low-dose daily tadalafil for years — not for the bedroom, but for the blood vessels. Most people think of these as sex drugs. I think of them as vascular drugs that happen to work below the belt. And a study published two weeks ago suggests they may do something nobody predicted: make it harder for cancer to spread. Here's the complete picture — the mechanism, the evidence, who should consider them, who absolutely shouldn't, and what I actually do.
- Aug 24, 20262.6x their median
% of people who would: * Try an “anti-aging” medicine: 61% * Take a cell reprogramming pill: 42% * Try a senolytic drugs: 27% * Have blood plasma diluted: 22% * Swap out their aged organs: 18% Surprisingly high percentages!
- Aug 2, 20262.3x their median
The difference between potentially living 20+ years longer is surprisingly simple. 1. Never smoking 2. At least 7.5 MET-hours/week (≈ 2h 15 min walking, 1 hour jogging, or 2.5 hours of weight training) 3. No excessive alcohol (<4 drinks/day for men, <3/day for women) 4. Sleep 7–9 hours 5. Healthy diet (top 40% of a healthy diet index) 6. Good stress management 7. Strong social connections 8. No opioid use disorder Among 276,000 US veterans, those who followed these 8 habits had an 87% lower risk of premature death and an estimated 24-year longer life expectancy compared to those following none. The benefits were dose-dependent: every additional healthy habit was associated with progressively longer life expectancy. Want to know what your health %-ile is? Take the quick assessment to get your score and find your biggest bottlenecks: https://t.co/6BrWir8FqN Study: PMID: 38065710
- Aug 4, 20262.2x their median
Rapamycin extends the lifespan of numerous species. A common “longevity” dose is 3 mg/once a week. New study reports a short-term rapamycin treatment (1 mg/d) improved immune & inflammatory markers, including reducing autoimmunity, but failed to reset the epigenetic clock https://t.co/3dX901wWco
- Aug 4, 20262.0x their median
Key players: Life Biosciences: first human dosing of a partial reprogramming therapy, targeting ophthalmology first BioAge Labs: IPO plus two Big Pharma collaborations validating its aging-biology data platform NewLimit: fastest capital velocity in epigenetic reprogramming, still pre-clinical Retro Biosciences: best-funded of the private reprogramming players, with a clearer path in autophagy than in reprogramming Altos Labs: launched in 2022 with the largest single commitment in the sector’s history ($3B), still without a disclosed clinical program Insilico Medicine: the AI-native, Asia-anchored platform play, positioning discovery speed as its edge https://t.co/ZuDpgoY0yR
- Aug 14, 20261.6x their median
Between July 16 and August 6, @FDA approved five medicines that had never existed before. Not five new drugs. Five firsts. 1. The first mRNA flu vaccine. Moderna’s mFlusiva, approved August 5 for adults 50 and up. In a trial of 40,805 people, it was 26.6% more effective than a standard flu shot. The technology that made the COVID vaccines now covers the flu. 2. The first drug that treats the cause of narcolepsy. Takeda’s Orzeyful, approved August 5. Narcolepsy type 1 occurs when the brain loses the cells that produce orexin, the neurotransmitter that keeps you awake. Every drug until now has papered over the sleepiness with stimulants. This one replaces the missing signal. 3. The first cholesterol pill in the PCSK9 class. Merck’s Lipfendra, approved July 16. It cuts LDL by 56 to 59%, matching the injectable antibodies, in a daily tablet. 4. The first over-the-counter Tylenol and naproxen combined in one pill. Approved July 24. Faster onset, 12 hours of relief. 5. A herpes virus, engineered to kill cancer, was approved on August 6 for advanced melanoma that stopped responding to immunotherapy. A quarter of those patients responded. Caveats: The melanoma approval is conditional on a confirmatory trial, and the new cholesterol pill has not yet proven that it prevents heart attacks, only that it lowers the number. Five firsts. Three weeks. Most of these drugs will be in pharmacies very soon.
- Aug 25, 20261.6x their median
Oral resveratrol for 32 weeks given to middle-aged mice reduced skin thinning, reversed the slowdown in skin cell division, reduced enzymes that break down collagen, and ostensibly activated SIRT1 😄 https://t.co/tk9ebIhCHM
- Aug 23, 2026
TECHbio: "we will cure all diseases in 5-10 years" BIOtech: "our candidate 1374 shows extraordinary early promise to lightly improve the standard of care in a single disease pending 8 more years of studies and 3 significant capital raises, public markets-willing"
Ranked by total interactions across everything we have tracked for this account, which is a longer history than the 30-day window the rates above use. The multiple compares each post to this account's own median.
Recurring topics
The most frequent hashtags in the sampled posts. They describe what this account writes about; they are not a performance signal, and the catalog-wide breakdown on the hub shows how little hashtag count moves.
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Reading these numbers
A typical post picks up 595 interactions against 657K followers, an engagement rate of 0.091%. Measured over 29 original posts, its engagement rate beats 69% of 3,739 tracked accounts of a similar size, which puts it in the middle of its size range rather than at either end. Posts are seen about 84K times each, and 0.707% of those impressions turn into an interaction. That is about 12.8% of the follower count, which is the gap between an audience on paper and an audience in a timeline. Posting runs at about 2.9 posts a day over the last 30 days, with activity on roughly 73% of days. Most posts go out around 16:00 UTC, and Tuesday is the busiest day of the week. Of the 29 posts sampled, 62% carry an image or video, 17% are part of a thread and 45% link out. The account's strongest tracked post pulled 6.4K interactions, about 11x its own typical post. Recurring topics include #amputation, #regeneration.
- What is David Sinclair's engagement rate on X?
- David Sinclair (@davidasinclair) has an engagement rate of 0.091%, based on the median interactions across 29 original posts from the last 30 days against 656,586 followers. Replies, reposts and quote-posts of other people are excluded from that sample.
- Is that a good engagement rate?
- At 0.091%, David Sinclair sits above the 50th percentile of the 36,378 accounts in this comparison. Those comparison accounts are all large ones, because our scanning cadence is weighted towards big accounts, so this is a ranking among peers of similar scale rather than a ranking across X.
- Does @davidasinclair have real engagement?
- Its engagement rate beats 69% of the tracked X accounts closest to it in follower count (3,739 accounts), which puts it in the middle of its size range group. Ranking inside a size band matters because engagement rate falls as accounts grow, so a raw rate would mostly re-measure the follower count. It is a starting point for a look at follower quality, not a verdict on it.
- When does @davidasinclair post?
- Most posts go out around 16:00 UTC, and Tuesday is its busiest day, at roughly 2.87 posts per day across the measured window.